đ Weekly: Hot and bothered
And biologically wired for it

WHATâS ON DECK
Tell Me More: The science behind why you canât âjust relaxâ
FQ Leaders Spotlight: Julie Lyle, President, TCC Global
Inside Track: Leaders on the move
Dear FQ: How do I ask for help at work without hurting my credibility?
Poll the Pack: The first 10 minutes of your day
TELL ME MORE
The stress mess

Youâre stuck in traffic and running late. A deadline is creeping up. You just had an argument with a friend. Stress shows up every day, and your body feels it instantly. Itâs an evolutionary reflex meant to keep us safe, but it can also take a toll, affecting women more than men.
Letâs break it down. There are 3 types of stress:
Acute: short-term and not always negative, just ask any thrill-seeker (hello, adrenaline)
Episodic acute: the daily stress that doesnât let up, not giving the mind and body a chance to recuperate
Chronic: long-term, and where real health issues start to show up
Most people know the âfight-or-flightâ response, coined by Dr. Walter B. Cannon in 1933. Itâs the bodyâs reaction to a perceived danger, a hard-wired survival mechanism that prepares the body to either confront or flee from threats. Cue The Clash, Should I Stay or Should I Go đś
Women are about 30% more likely than men to live in chronic fight-or-flight mode. Part of that is biological. Women have a stronger stress hormone response and more sensitive receptors. Even in studies with rats, females not only react more intensely to stress, but also take longer to recover. When exposed to stress, both male and female rats release the hormone corticotropin-releasing factor (CRF), but thereâs a big difference. Female rats release more of the receptor CRF1, while male rats release more of the variant CRF2. Hereâs the kicker: CRF1 initiates the bodyâs stress response, while CRF2 finishes it, so not only are female rats more primed to be stressed, they take a longer time to recover. In humans, that shows up in real ways: higher rates of PTSD, anxiety, and depression in women.
But itâs so much more than biology that makes women susceptible. Thereâs an intersection of cultural expectations, habitual over-giving, and generations of conditioning to âpush through.â And for years, research assumed women responded to stress the same way men do.
That changed when UCLA psychologist Shelley Taylor introduced âtend and befriend.â She found that women often respond to stress by caring for others and seeking connection. Itâs not weakness; itâs biology. Forming these bonds in the face of stress helps reduce its impact. Through the release of the hormone oxytocin, womenâs bodies have found a way to soothe themselves with emotional connection.
Still, for the 30% of women who are chronically in fight-or-flight, that regulation doesnât come easily. When your body is stuck in fight-or-flight, itâs focused on survival, and everything else gets deprioritized: hormones, immune function, recovery, and even memory. Says Lily Brown, Director of the Center for the Treatment and Study of Anxiety at the University of Pennsylvania, âWhat we often see clinically is that people arenât reacting only to the event in front of them. Theyâre reacting to a whole history of stress that has already taxed their system. By the time a major stressor hits, the brain and body may already be operating under a heavy load.â This can cause insomnia, fatigue, acne, headaches, forgetfulness (which, in stressful situations, has been linked to estrogen), dementia, hair loss, irregular periods, fertility issues, and the list goes onâŚ
But hereâs the powerful, and very important, part: regulation is learnable. When you teach your nervous system itâs safe, everything changes: your energy, focus, mood, health, and capacity to lead. Be aware of what is causing you stress, and give yourself agency to address it. Exercise, do breath work, go to therapy, explore creative hobbies, get outside, eat nourishing food, connect with friends, and get a good nightâs sleep. These arenât just basic self-care practices. Theyâre strategic, science-backed acts to a calm nervous system. If women want greater health and longevity, we cannot afford to wait for science to catch up. When it comes to how we respond to stress, there can only be one option: fight.
FQ LEADERS SPOTLIGHT
Troublemakers who donât fit the mold, and donât try to

Julie Lyle is a Board Director at Dstillery, the leading predictive AI audience targeting company. She is also President and Board member of TCC Global, where she leads efforts to help retailers around the world drive customer loyalty, data strategy, and marketing programs at scale. Julie began her career as an entrepreneur before moving into executive roles at Walmart, Prudential plc, and Barnes & Noble, building deep expertise at the intersection of commerce and consumer behavior. In addition to her operating roles, she is a seasoned investor and advisor, serving on the board of meetsynthia.ai. Julie is widely recognized for her perspective on how brands can build lasting customer relationships through data and personalization.
Whatâs the most unexpected opportunity youâve gotten in your career?
Early in my career, Mitch Hart, who is a venture capitalist and Founder of The Hart Group, recognized my potential and gave me the role of functionally reporting to 5 portfolio company CEOs, while administratively reporting to Mitch as Chairman. Through that job, I learned to successfully navigate internal politics, build trust among competing executives, and master conflict among big personalities. It was challenging, and the skills I gained were invaluable.
Whatâs the worst career advice youâve gotten?
âIf people allow you to take advantage of them, they deserve what they get.â I categorically disagree with that. I believe we all have a moral imperative to do well by doing good, as companies and as people. At the end of the day, your integrity is all that matters.
What was a heartbeat moment for you in your career?
It was when my mother was diagnosed with cancer. While she fought valiantly, she eventually had to be transitioned to hospice care. I was CMO of Walmart at the time, and I immediately resigned so that I could go and take care of her. It was a heartbeat moment for me because I loved my job. It was difficult to go from managing multi-billion-dollar profit and loss statements to changing bedpans and IVs, but I wouldnât change that decision for the world. Those last months I had with my mom will always be precious to me.
Who is one person youâd love to give flowers to from your career that influenced your journey? What advice or lesson did you learn from them?
I would give flowers to Dan Burnham, who, when he was CEO at Raytheon, gave me a âtough loveâ challenge to be more intentional about how I managed my career. I took his advice to heart and developed a 7-part marketing plan with time and action schedules that I implemented and followed for the next 25 years. It had an incredible impact on my career growth and income. I eventually turned it into a curriculum and convinced Walmart to offer the program to 2,500 female managers in an effort to empower them with a clear path for growth and development. Even though it was 18 years ago, I still receive notes from women who used those growth insights to achieve success. Iâm grateful to Dan for challenging me, bringing out my best, and allowing me to pay it forward.
Where have you caused some good trouble in your career?
During the 2008 global financial crisis, I was leading a team charged with accelerating growth in Prudentialâs Asian insurance business. Market confidence was at an all-time low, and we had very little brand awareness in Asia. After careful research, we went against industry standards and took a big risk. We shifted our entire marketing strategy from typical financial services messaging to focus on families with children under the age of 12. We developed music videos, apps, games, and characters around a financial learning program for kids. We shifted our advertising dollars from the major news and financial media outlets to Nickelodeon. It was a huge success, and our sales, recruitment, and brand recognition soared.
Want to nominate a âTroublemakerâ you admire? You can do so here.
INSIDE TRACK
Leaders on the move
Julie Yufe has taken on the role of EVP and Managing Director International at the National Hockey League (NHL)
Agnès Pinel is now Chief Human Resources Officer at Parfums Christian Dior and LVMH Beauty Division
Allison Giorgio has been appointed Chief Marketing Officer at NOBULL
Anna Frost is now Head of Marketing at CNN Worldwide
Michele Griffin has joined Lightning Capital as General Partner and COO
Jessica Williams has stepped into the role of Chief Marketing Officer role at OnePay
DEAR FQ
Your burning career questions answered

Margot Rathke of The Female Quotient weighs in:
Weâve all been there. You want to seem confident and competent, so you donât ask for help. But hereâs the reframe: requesting support isnât proof that you donât know what youâre doing. It shows that you are eager to learn, value feedback, and are committed to turning out high-quality work. Research backs this up. Studies have shown that people who ask for advice are perceived as more competent, not less. Why? Because theyâre engaged, thoughtful, and invested in the outcome. By asking for clarity, youâre ensuring that you are aligned with your colleagues. And practically speaking, a five-minute check-in can save hours of rework.
That said, resourcefulness is one of the most underrated skills (in work and life!). Do the homework first. Show youâve thought it through. Do as much troubleshooting on your own before approaching a colleague. And remember that the âwhat ifsâ and âwhysâ are often what spark innovation. They challenge âthe way itâs always been doneâ and can lead to smarter, more efficient ways of working. A simple question could be an opportunity for growth for you and the company.
P.S. Got a burning career question? Serve it up here to Dear FQ to score advice from a powerhouse leader in our network.
POLL THE PACK
Revving up for the day
Humans are creatures of habit. The routines we build can reduce stress while setting the tone for how we show up at work. Employees were nearly split between starting the day with coffee and quiet time and diving straight into email. Itâs a small choice, but it reflects a bigger divide: those creating intentional space, and those pulled immediately into reaction mode.
When 38% of people start with email, it points to a broader pattern: responsiveness is prioritized over reflection. Urgency gets mistaken for importance and we end up in a culture of constant reaction instead of intentional action.
Taking even a moment to reflect and recalibrate creates clarity. Think of the start of your day as something worth reclaiming. It sets the foundation for everything that follows.
Breathe in, breathe out. You got this đ§ââď¸
Xo,
The FQ
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